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近年来,冠心病发病机理的研究取得很大的进展。除动脉粥样硬化病灶外,认识到血小板聚集和冠状动脉痉挛是致病的另二个重要病理现象。尽管对这些病理现象的发生机制还不完全清楚,但是随着对血小板-血管壁相互作用以及对前列腺素代谢的病理生理意义的深入了解,血小板在冠心病发生和发展中的重要地位再次受到重视。血小板在动脉粥样硬化和动脉血栓形成中的作用流行病学调查发现,长期服用阿斯匹林
In recent years, the pathogenesis of coronary heart disease made great progress. In addition to atherosclerotic lesions, it is recognized that platelet aggregation and coronary artery spasm are the other two important pathogenic pathologies. Although the pathogenesis of these pathologies is not yet fully understood, the importance of platelets in the development and progression of coronary heart disease has received renewed attention with its deep understanding of the platelet-vascular wall interactions and the pathophysiological significance of prostaglandin metabolism . Role of platelets in atherosclerosis and arterial thrombosis Epidemiological survey found that long-term use of aspirin