苯为造血系统毒物,慢性苯中毒可见血细胞再生障碍,其中以白细胞减少最为多见。但是苯对白细胞质的变化,迄今文献报道尚少。我们自1972年以来曾从粒细胞退行性变、硷性磷酸酶活性和吖啶橙荧光染色等不同方面观察苯对白细胞的毒性作用;发现慢性苯中毒或苯接触工人的中性粒细胞都有退行性核象左移,胞浆内毒性颗粒增多,说明苯 Benzene is a hematopoietic system toxicants, chronic benzene poisoning can be seen in blood cell aplasia, of which the most common leukopenia. However, the change of benzene on the white cytoplasm has not been reported in the literature so far. We have observed the toxic effects of benzene on white blood cells from different aspects of granulocyte degeneration, alkaline phosphatase activity and acridine orange fluorescence staining since 1972. We found that both chronic benzene poisoning and benzene exposed workers have neutrophils Left degenerative nuclear imaging, intracytoplasmic toxic particles increased, indicating benzene