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目的探讨早期区域动脉灌注治疗急性重症胰腺炎的临床疗效。方法对10例急性重症胰腺炎患者采用区域动脉早期灌注治疗,并进行回顾性分析。结果经区域动脉灌注后第1、3天,白细胞计数分别为(16.42±3.45)×109/L,(13.79±3.23)×109/L;血淀粉酶分别为(303.4±297.6)U/L,(155.4±195.6)U/L;灌注治疗后第1天尿淀粉酶为(487.5±121.5)。均较治疗前明显下降。8例病人(80%)灌注治疗后第3天腹痛明显缓解。全组平均住院时间14.3天,联合手术1例。病死率10%(1/10)。结论早期区域动脉灌注可作为急性重症胰腺炎的安全有效的治疗手段。
Objective To investigate the clinical efficacy of early regional arterial infusion in the treatment of acute severe pancreatitis. Methods Ten patients with severe acute pancreatitis were treated with regional arterial infusion and analyzed retrospectively. Results The counts of white blood cells were (16.42 ± 3.45) × 109 / L and (13.79 ± 3.23) × 109 / L on day 1 and day 3, respectively. The blood amylases were (303.4 ± 297.6) U / L, (155.4 ± 195.6) U / L, urinary amylase was (487.5 ± 121.5) on the first day after perfusion. Significantly lower than before treatment. Eight patients (80%) were significantly relieved of abdominal pain on day 3 after perfusion. The average hospital length of stay 14.3 days, combined surgery in 1 case. Case fatality rate 10% (1/10). Conclusion Early regional arterial infusion can be used as a safe and effective treatment for acute severe pancreatitis.