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本实验采用C-反应蛋白、α_2巨球蛋白和纤维结合蛋白等三个实验室指标探讨其对急性胰腺炎的诊断和判断作用。实验结果表明,C-反应蛋白在急性胰腺炎中含量增高,而α_2巨球蛋白、纤维结合蛋白在急性胰腺炎中含量降低。通过对三种蛋白变化率的百分计算,可对坏死型胰腺炎和重型胰腺炎作早期的判断,其在入院后3天诊断的敏感度、特异性、阳性及阴性预告值在前者可达86%、93%、92%、88%,在后者可达100%、96%、83%、100%,因此对临床的辅助诊断、判别有很大的作用。
In this study, C-reactive protein, α 2 macroglobulin and fibronectin and other three laboratory indicators to explore its diagnosis and judgment of acute pancreatitis. Experimental results show that C-reactive protein increased in acute pancreatitis, while α 2 macroglobulin, fibronectin in acute pancreatitis decreased. Through the percentage change of the three kinds of protein, early judgment of necrotizing pancreatitis and severe pancreatitis can be made. The sensitivity, specificity, positive and negative predictive value of diagnosis on the 3rd day after admission are reachable in the former 86%, 93%, 92%, 88%, in the latter up to 100%, 96%, 83%, 100%, so the clinical diagnosis and identification of a great role.