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作者报道32例十二指肠溃疡病人,早餐前15分钟空腹1次口服甲氧磺唑(omeprazole)20毫克(16人),60毫克(16人),连续4周。内窥镜检查证实溃疡治愈率:2周时,60毫克组为100%,20毫克组为63%;第4周20毫克组为93%。说明60毫克组比20毫克组治愈率明显增高。两组比较P<0.02。
The authors reported 32 patients with duodenal ulcer who were orally given omeprazole 20 mg (16) and 60 mg (16) orally for 15 minutes before breakfast for 4 weeks. Endoscopy confirmed ulcer cure rates: at 2 weeks, the 60 mg group was 100%, the 20 mg group was 63%; the 4th week 20 mg group was 93%. Description 60 mg group than the 20 mg group was significantly higher cure rate. P <0.02 for both groups.