论文部分内容阅读
头孢三嗪是第三代广谱头孢菌素,对β-内酰胺酶稳定,血浆消除半衰期长,杀菌有效浓度达24小时,可以迅速透入全身各组织和体液,使大多数病灶中的药物浓度达到或者超过革兰氏阳性菌和阴性菌等大多数菌株的 MIC 的几倍。一直到1987年的中期,总计发表有关头孢三嗪的论文多达2346篇,其中有关临床研究的论文486篇,包含该药治疗病例达32000例,其中单用头孢三嗪的病例有20628例,与头孢三嗪合并治疗的病例有1346例,应用
Ceftriaxone is the third generation of broad-spectrum cephalosporins, β-lactamase stability, long half-life of plasma elimination, sterilization effective concentration of up to 24 hours, can quickly penetrate the body tissues and body fluids, so that most of the lesions in the drug The concentration reached or exceeded several times the MIC of most strains such as Gram-positive bacteria and Negative bacteria. Until the mid-1987, a total of 2346 articles on ceftriaxime were published, of which 486 were papers on clinical research, including 32,000 cases of the treatment of this drug, including 20,628 cases of ceftriaxone alone, There are 1346 cases of combined treatment with ceftriaxone, application