论文部分内容阅读
目的:研究母乳中多溴联苯醚的污染水平和特征。方法:母乳经冻干后,加入同位素内标,经索氏抽提萃取,再经一系列色谱柱净化,用气相色谱-高分辨磁质谱测定,同位素内标法定量分析母乳中的PBDE残留。结果:母乳中23种PBDE的总浓度均值为1497±584 pg/g lipid(831-2814 pg/g lipid);PBDE-153(20.94%),PBDE-47(18.34%),PBDE-15(13.35%),PBDE-28(12.39%),PBDE-183(8.43%)依次是检出浓度最高的五种单体。结论:绍兴母乳中PBDEs的含量与国内其它报道的数据接近,但低于发达国家报道的水平;推测除膳食摄入外,呼吸也是人体暴露PBDEs的主要途径。
Objective: To investigate the level and characteristics of polybrominated diphenyl ethers in breast milk. Methods: After the milk was lyophilized, the internal standard of isotope was added. The extract was extracted by Soxhlet extraction and purified by a series of column chromatography. The content of PBDE in breast milk was quantitatively determined by gas chromatography - high resolution mass spectrometry and isotope internal standard method. RESULTS: The mean concentrations of 23 PBDEs in breast milk were 1497 ± 584 pg / g lipid (PBDE-153), PBDE-47 (18.34%) and PBDE-15 %), PBDE-28 (12.39%), PBDE-183 (8.43%) followed by the highest concentration of the five detected monomers. Conclusion: The content of PBDEs in breast milk of Shaoxing is close to that of other reported data in China, but it is lower than that reported in developed countries. It is speculated that besides the dietary intake, respiration is also the main way to expose PBDEs.