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目的:探究C反应蛋白与心脑血管疾病的相关性。方法:对2011年1月～2013年1月500例本院内科收治的心脑血管疾病患者同时检测血脂、血糖、C反应蛋白水平,根据疾病情况分为轻、中、重组,分析评价心脑血管疾病的相关危险因素,并比较心脑血管疾病不同病情轻重之间C反应蛋白的水平。结果:除年龄、高血压、糖尿病、血脂异常等危险因素外,C反应蛋白同样是心脑血管疾病的独立危险因素。轻度心脑血管疾病组、中度心脑血管疾病组、重度心脑血管疾病组C反应蛋白水平分别是16.6+8.5mg/d1、38.7+6.8mg/d1、57.6+6.4mg/d1各组之间比较差异有统计学意义(P<0.05)。结论:C反应蛋白是心脑血管疾病的独立危险因素,且水平可提示疾病的严重程度。
Objective: To investigate the correlation between C-reactive protein and cardiovascular and cerebrovascular diseases. Methods: From January 2011 to January 2013, 500 patients with cardiovascular and cerebrovascular diseases admitted to our hospital were enrolled in the study. Blood lipids, blood glucose and C-reactive protein were detected simultaneously. The patients were divided into mild, moderate and severe cases according to the disease status, Vascular disease risk factors, and compare the severity of cardiovascular disease between C-reactive protein level. Results: Except for risk factors such as age, hypertension, diabetes and dyslipidemia, C-reactive protein was also an independent risk factor for cardiovascular and cerebrovascular diseases. The levels of C-reactive protein in mild cardiovascular and cerebrovascular disease group, moderate cardiovascular disease group and severe cardiovascular and cerebrovascular disease group were 16.6 ± 8.5mg / d1, 38.7 ± 6.8mg / d1 and 57.6 ± 6.4mg / d1 The difference was statistically significant (P <0.05). Conclusion: C-reactive protein is an independent risk factor for cardiovascular and cerebrovascular diseases, and the level can indicate the severity of the disease.