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目的探讨埃索美拉唑与奥美拉唑治疗胃溃疡的效果对比。方法以均等随机分组原则对我院接治的胃溃疡106例患者进行组别划分,两组患者均给予克拉霉素、阿莫西林治疗,其中对照组53例患者在此基础上联合奥美拉唑治疗,观察组则联合埃索美拉唑治疗。观察两组患者的治疗效果及Hp根除情况。结果观察组的临床总有效率明显高于对照组,P<0.05;观察组患者的Hp根除率明显高于对照组,P<0.05。结论采用埃索美拉唑对胃溃疡患者进行治疗的效果较奥美拉唑更好,并且能更加有效地根除幽门螺杆菌,值得进一步推广。
Objective To compare the efficacy of esomeprazole and omeprazole in the treatment of gastric ulcer. Methods According to the principle of equal randomization, 106 patients with gastric ulcer treated in our hospital were divided into groups. Patients in both groups were treated with clarithromycin and amoxicillin. In the control group, 53 patients were combined with omeprazole Azole treatment, the observation group was combined with esomeprazole treatment. The therapeutic effect and eradication of Hp in both groups were observed. Results The total clinical effective rate in the observation group was significantly higher than that in the control group (P <0.05). The Hp eradication rate in the observation group was significantly higher than that in the control group (P <0.05). Conclusion The effect of esomeprazole on patients with gastric ulcer is better than that of omeprazole, and Helicobacter pylori can be eradicated more effectively, which deserves further promotion.