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人类细胞色素Ｐ４５０酶系选择性催化药物代谢与其毒性的关系ＧｕｅｎｇｅｒｉｃｈＦＰ细胞色素Ｐ４５０（Ｐ４５０）是催化药物氧化的主要酶系。主要存在于肝脏中，但肝外组织亦含此酶，有时对药物氧化也起重要作用。各种动物都有许多不同的Ｐ４５０酶，已知人类至少有２...
Selective Catalytic Metabolism of Human Cytochrome P450 Enzyme and Its Toxicity GuengerichFP Cytochrome P450 (P450) is a major enzyme that catalyzes the oxidation of drugs. Mainly in the liver, but extrahepatic tissue also contains this enzyme, and sometimes the drug also plays an important role in oxidation. Various animals have many different P450 enzymes, known to humans at least 2 ...