论文部分内容阅读
目的:探讨为1000例狂犬病暴露者接种狂犬疫苗的临床效果。方法:对2013年2月~2013年8月期间我中心收治的1000例狂犬病暴露者的临床资料进行回顾性研究。这1000例狂犬病暴露者中包括458例女性患者和542例男性患者。我们为这1000例狂犬病暴露者接种狂犬疫苗15天后,为其抽血化验狂犬病病毒中和抗体的效价,观察并分析患者接种狂犬疫苗后的临床效果。结果:接种疫苗后,患者的血清抗体检测总转阳率达90.8%(女性略高于男性),其中男性的抗体阳性率为88.9%,女性的抗体阳性率为91.4%,高龄患者的抗体阳性率为82.1%。接种疫苗后,患者不良反应的发生率为5.3%。结论:为狂犬病暴露者接种狂犬疫苗有助于狂犬病的预防。
Objective: To investigate the clinical effect of vaccinating rabies vaccine for 1000 rabies exposed persons. Methods: A retrospective study was conducted on the clinical data of 1000 rabies exposed patients admitted to our center from February 2013 to August 2013. Among the 1,000 cases of rabies exposure, 458 were female and 542 were male. After we vaccinated rabies vaccine for these 1000 rabies exposed for 15 days, we tested the clinical efficacy of rabies vaccine neutralizing antibodies against blood tests. RESULTS: After vaccination, the total positive rate of seroconversion in patients was 90.8% (slightly higher in women than in men), of which 88.9% were male, 91.4% were female, and those in elderly were positive The rate was 82.1%. After vaccination, the incidence of adverse reactions in patients was 5.3%. Conclusions: Vaccination with rabies vaccines for rabies exposure contributes to rabies prevention.