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Rho蛋白是一种小分子G蛋白(small G protein,GTPase),其最重要的功能是调节肌动蛋白细胞骨架,从而参与细胞迁移、调控肿瘤转移,因此,Rho蛋白与消化系统恶性肿瘤侵袭与转移的关系,已成为研究的前沿领域之一。1Rho蛋白及其信号转导通路哺乳动物Rho蛋白至少包括以Rho(RhoA、RhoB、
Rho protein is a small G protein (GTPase) whose main function is to regulate the actin cytoskeleton, which is involved in cell migration and regulate tumor metastasis. Therefore, Rho protein is associated with the invasion of digestive system malignancies The transfer of relations has become one of the frontiers of research. 1 Rho protein and its signal transduction pathway mammalian Rho proteins include at least Rho (RhoA, RhoB,