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目的 研究马尔尼菲青霉菌感染竹鼠的组织病理学方法。方法 应用HE ,Grocotte ,免疫组化染色及电镜观察。结果 马尔尼菲青霉菌引起竹鼠各脏器的组织病理学改变为化脓性病变及肉芽肿性病变 ,病变轻微。结论 竹鼠为马尔尼菲青霉菌的天然储库。主要侵犯竹鼠的肺和单核巨噬细胞系统。
Objective To study the histopathology of Penicillium marneffei infected bamboo shoots. Methods HE, Grocotte, immunohistochemistry and electron microscopy were used. Results Penicillium marneffei caused histopathological changes in each organ of bamboo rats as purulent and granulomatous lesions with slight lesion. Conclusion The bamboo rat is a natural reservoir of Penicillium marneffei. Mainly infringe the bamboo rat lung and mononuclear macrophage system.