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该研究纳入参加随机对照试验——“控制糖尿病患者心血管风险行动”试验中的4331例糖尿病患者,比较强化治疗(收缩压<120 mm Hg,1 mm Hg=0.133kPa)与标准治疗(收缩压<140 mm Hg)的作用,探讨降压治疗对左心室肥厚(left ventricular hypertrophy,LVH)风险的影响。采用Cornell电压(二分类变量)及平均Cornell指数(连续变量)评估心电图LVH。基线时强化治疗组(n=2154)与标准治疗组(n=2177)的LVH发生率(5.3%比5.4%,P=
The study enrolled 4331 diabetic patients enrolled in a randomized controlled trial, the “Controlled Cardiovascular Risk Action for Diabetics” trial. Compared with standard therapy (systolic blood pressure <120 mm Hg, 1 mm Hg = 0.133 kPa) Systolic blood pressure <140 mm Hg) to investigate the effect of antihypertensive treatment on the risk of left ventricular hypertrophy (LVH). ECG LVH was evaluated using Cornell voltage (dichotomous variables) and mean cornell index (continuous variables). The incidence of LVH in the intensive-treatment group (n = 2154) and the standard treatment group (n = 2177) at baseline was 5.3% vs. 5.4%, P =