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A series of diclofenac derivatives were synthesized.The insulin-sensitizing activity of 28 new compounds was evaluated in 3T3- L1 cells.The compounds 10a and 10f exhibited similar insulin-sensitizing activity with positive drug rosiglitazone.
A series of diclofenac derivatives were synthesized. The insulin-sensitizing activity of 28 new compounds was evaluated in 3T3-L1 cells. Compounds 10a and 10f similar insulin-sensitizing activity with positive drug rosiglitazone.