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目的分析研究尤瑞克林在治疗急性前循环脑梗死方面的近期临床效果。方法 58例急性前循环脑梗死患者,随机分为观察组和对照组,每组29例。两组患者均给予常规对症治疗,在此基础上,观察组添加尤瑞克林治疗,对照组给予生理盐水做空白对照,对比两组患者的近期临床效果。结果对照组治疗前日常生活能力(m RS)评分为(4.07±0.15)分,神经功能缺损程度(NIHSS)评分为(5.21±2.36)分,治疗后分别为(2.30±1.56)、(3.73±1.90)分;观察组治疗前m RS评分为(4.00±0.16)分,NIHSS评分为(5.91±2.82)分,治疗后分别为(1.65±0.22)、(2.82±0.76)分。治疗前两组患者m RS和NIHSS评分比较差异无统计学意义(P>0.05);治疗后,两组患者m RS和NIHSS评分低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组治愈12例(41.4%),有效15例(51.7%),无效2例(6.9%),临床总有效率为93.1%,对照组治愈10例(34.5%),有效13例(44.8%),无效6例(20.7%),临床总有效率为79.3%;观察组临床总有效率明显高于对照组,差异具有统计学意义(P<0.05)。结论采用尤瑞克林治疗急性前循环脑梗死,临床总有效率高,近期效果好,可显著减轻脑梗死对患者神经功能的损伤,预后佳,是值得临床广泛推广应用的。
Objective To analyze the clinical effect of erilecin in the treatment of acute anterior circulation cerebral infarction. Methods 58 patients with acute anterior circulation cerebral infarction were randomly divided into observation group and control group, with 29 cases in each group. Two groups of patients were given conventional symptomatic treatment, on this basis, the observation group added uricocaine treatment, the control group given saline as a blank control, compared the two groups of patients in the near future clinical results. Results The m RS score and the NIHSS score before treatment were (5.21 ± 2.36) and (2.30 ± 1.56, 3.73 ± 1.90). The score of mRS in the observation group before treatment was (4.00 ± 0.16) points, NIHSS score was (5.91 ± 2.82) points after treatment, respectively (1.65 ± 0.22) and (2.82 ± 0.76) points after treatment. There were no significant differences in m RS and NIHSS scores between the two groups before treatment (P> 0.05). After treatment, m RS and NIHSS scores of both groups were lower than those before treatment, and the observation group was lower than the control group Significance (P <0.05). The observation group was cured in 12 cases (41.4%), effective in 15 cases (51.7%), ineffective in 2 cases (6.9%), clinical total effective rate was 93.1%, control group cured in 10 cases (34.5% ), 6 cases (20.7%) were ineffective, and the total clinical effective rate was 79.3%. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). Conclusion The treatment of acute anterior circulation cerebral infarction with ureclins has high total effective rate and good effect in the near future. It can significantly reduce the neurological deficits in patients with cerebral infarction. The prognosis is good and should be widely applied clinically.