许多作者已证实用血清学技术能检测血吸虫病人及动物体内的循环抗原。本文作者对感染埃及血吸虫及用药物治疗的狒狒,用酶联免疫吸附试验(ELISA)检测其体内的循环抗原和抗体。并用集卵及解剖灌注法收集虫体进行对照。实验用4只狒狒,每只狒狒大约用7,000条埃及血吸虫尾蚴经肤感染。于22周后对其中3只应用硝唑咪,硝硫氰胺及苯二氮嗪衍生物进行治疗。另一只狒狒不治疗作为对照。感染动物每周进行2次虫卵计数,每月抽血一次,分离的血清,保存于-20℃内。治疗的3只动物于治后3～4个月进行解剖,用灌注 Many authors have demonstrated that serological techniques can be used to detect circulating antigens in schistosomiasis patients and animals. The author of the infection of schistosomiasis and drug treatment of baboons by enzyme-linked immunosorbent assay (ELISA) detection of circulating antigens and antibodies in vivo. Collect the parasites and control them by collecting eggs and dissecting perfusion. Four baboons were used in the experiment, and about 80,000 babies were skin-infected with about 7,000 S. japonicum cercariae. Three of them were treated with nitazoxanide, nitrofurazone and benzodiazepine derivatives after 22 weeks. Another baboon was not treated as a control. Infected animals were counted twice a week eggs, blood draw once a month, isolated serum, stored at -20 ℃. The three animals treated were dissected 3 to 4 months after treatment and were perfused