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人类感染乙型肝炎病毒(HBV)时,往往抗-HBc持续存在。因此,抗-HBc出现是HBV感染或曾感染的最可靠标志,亦可能是以往感染的唯一标志。本文报道9例ALT正常的慢性HBV携带者,其血清中缺乏抗-HBc,但存在大量HBcAg和HBV DNA。 20例在首次检查时HBsAg阳性而抗-HBc阴性的患者中,10例患者临床均恢复,抗-HBc在转氨酶升高时出现阳性,接着HBsAg转阴,抗-HBs阳性,其中5例在急性期前所取的血清标本作为对照;另10例抗-
When humans are infected with hepatitis B virus (HBV), anti-HBc is often persisted. Therefore, anti-HBc is the most reliable indicator of HBV infection or infection, may also be the only sign of previous infection. This article reports 9 cases of normal ALT chronic HBV carriers, the lack of serum anti-HBc, but there is a large number of HBcAg and HBV DNA. Of the 20 patients with HBsAg-positive and anti-HBc-negative at initial examination, 10 patients recovered clinically. Anti-HBc was positive when transaminases were elevated, followed by HBsAg negative and anti-HBs positive, of which 5 were acute Serum samples taken before the period as a control; the other 10 cases of anti-