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植物雌激素是一类具有类似动物雌激素生物活性的植物成分,大量实验室资料及流行病学调查表明植物雌激素对人体心血管系统具有广泛的雌激素样保护作用而危险性相对较低,其机制可能与抑制血管平滑肌细胞增生和DNA合成、抗氧化和过氧化损伤、降血脂及血浆脂蛋白、增加血管顺应性、扩张硬化血管以及抗高血压等作用有关。越来越多研究表明雌激素有可能成为一种安全有效的雌激素替代药物用于心血管疾病的防治。
Phytoestrogens are a class of plant components that have similar animal estrogenic biological activity. A large number of laboratory data and epidemiological investigations show that phytoestrogens have a relatively low risk of having extensive estrogen-like protective effects on human cardiovascular system, The mechanism may be related to the inhibition of vascular smooth muscle cell proliferation and DNA synthesis, anti-oxidative and peroxidative damage, hypolipidemic and plasma lipoprotein, increased vascular compliance, expansion of sclerosing blood vessels and antihypertensive effects. More and more research shows that estrogen may become a safe and effective estrogen replacement medicine for the prevention and treatment of cardiovascular diseases.