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目的分析检测血清降钙素原(PCT)与超敏C-反应蛋白(hs-CRP)对肿瘤晚期患者感染与肿瘤热的临床诊断意义。方法将收治的113例肿瘤晚期患者作为研究对象,根据其发热类型分为无发热患者A组27例,肿瘤性发热为B组33例,细菌感染性发热为C组53例,对比分析三组患者的相关指标。结果 C组患者的PCT水平显著高于A组和B组(P<0.05),hs-CRP、NEUT、NEUT%、WBC等指标三组相比无差异(P>0.05),经过治疗后,三组患者各项指标的变化情况显示,C组患者PCT水平升高率显著高于A组和B组(P<0.05),其他各项指标的升高率情况相比无差异(P>0.05)。结论 PCT对于临床上肿瘤热与细菌感染性发热的鉴别意义重大,hs-CRP、NEUT、NEUT%、WBC等指标用于鉴别肿瘤热与细菌感染性发热时无显著性意义。
Objective To analyze the clinical significance of detecting serum procalcitonin (PCT) and high sensitivity C-reactive protein (hs-CRP) in the diagnosis of advanced cancer patients with tumor infection and tumor heat. Methods A total of 113 patients with advanced cancer were enrolled in this study. According to the type of fever, they were divided into group A (n = 27), group B (n = 33), bacterial infection (group C: n = 53) Patient-related indicators. Results The PCT level in group C was significantly higher than that in group A and group B (P <0.05). There was no difference between the three groups in hs-CRP, NEUT, NEUT% and WBC (P> 0.05) The change of each index of patients in group C showed that the increase rate of PCT level in group C was significantly higher than that in group A and B (P <0.05), while there was no difference in the rate of increase of other indexes (P> 0.05) . Conclusion PCT is of great significance for the differential diagnosis of clinical fever and bacterial infectious fever. The indexes of hs-CRP, NEUT, NEUT% and WBC are not significant for differentiating the fever from bacterial infection.