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目的:探讨心脏标志物肌钙蛋白I(CTnI)和D-二聚体(D-DI)联合检测在急性心肌梗死(AMI)诊断中的作用。方法:回顾性分析2010年1月至2011年9月广东省人民医院收治286例急性心源性胸痛患者临床资料,根据病情及入院24 h内的CTnI水平的不同将患者分为2组:A组(急性心肌梗死且CTnI水平≥0.5μg/L,48例),B组(经临床确诊为心绞痛且CTnI水平<0.5μg/L,238例)。比较两组患者D-DI水平的不同。结果:A、B两组患者的血清D-DI水平分别为(333.1±857.98)、(157.0±12.9)μg/L,两组比较,差异有统计学意义(P<0.05)。结论:CTnI和D-DI联合检测更有利于AMI的诊断和预后判断。
Objective: To investigate the combined effect of cardiac troponin I (CTnI) and D-dimer (D-DI) in the diagnosis of acute myocardial infarction (AMI). Methods: The clinical data of 286 patients with acute cardiogenic chest pain admitted to the Guangdong Provincial People’s Hospital from January 2010 to September 2011 were retrospectively analyzed. Patients were divided into two groups according to their severity and the level of CTnI within 24 hours of admission: A Group C (angina pectoris and CTnI level <0.5μg / L, 238 cases) were in group A (AMI with CTnI≥0.5μg / L, 48 cases). The differences in D-DI levels between the two groups were compared. Results: The levels of serum D-DI in the two groups were (333.1 ± 857.98) and (157.0 ± 12.9) μg / L, respectively. There was significant difference between the two groups (P <0.05). Conclusion: The combined detection of CTnI and D-DI is more beneficial to the diagnosis and prognosis of AMI.