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目的：研究缺血性脑血管病与椎基底动脉血流动力学改变的关系。方法：对４２例老年缺血性脑血管病患者颅内外动脉血流速度进行经颅多普勒超声监测分析。结果：（１）椎基底动脉与颈内动脉相比，血流速度降低具有显著性差异（Ｐ＜０．０１）。（２）短暂性脑缺血发作在椎基底动脉血流速度高低范围内均可发作，而脑血栓形成及多发性腔隙性梗死则集中在椎基底动脉低血流速度范围内。（３）椎基底动脉血流速度降低与脑梗死发病率呈正相关（ｒ＝０．９９８３，Ｐ＜０．０５）。结论：椎基底动脉缺血严重的患者有发生脑梗死的高度危险性。
Objective: To study the relationship between ischemic cerebrovascular disease and hemodynamics of vertebrobasilar artery. Methods: The intracranial and extracranial arterial blood flow velocities in 42 elderly patients with ischemic cerebrovascular disease were analyzed by transcranial Doppler ultrasonography. Results: (1) Compared with the internal carotid artery, vertebrobasilar artery had a significant difference in blood flow velocity (P <0.01). (2) Transient ischemic attack may occur in the vertebrobasilar artery blood flow velocity range, while cerebral thrombosis and multiple lacunar infarction are concentrated in the low blood flow velocity range of vertebrobasilar artery. (3) The decrease of vertebrobasilar blood flow velocity was positively correlated with the incidence of cerebral infarction (r = 0.9983, P <0.05). Conclusion: Patients with severe ischemia of vertebrobasilar artery have a high risk of developing cerebral infarction.