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目的:探讨老年2型糖尿病肾病并发心脑血管疾病的一些相关危险因素,为临床治疗和干预提供理论依据。方法:选取350例2型糖尿病肾病合并心脑血管疾病老年患者作为研究对象,根据2型糖尿病肾病和心脑血管疾病分级标准将患者有无糖尿病肾病并发心脑血管疾病分为并发组148例和未并发组202例。比较两组受检者的调查数据如性别比例、年龄、吸烟人数、饮酒人数、饮食喜好、饮食规律和检测指标如体重指数(BMI)、收缩压(SBP)、舒张压(DBP)、脉压差(PP)、病程、同型半胱氨酸(HCY)、空腹血糖(FPG)及甘油三酯(TG)、胆固醇(TC)、糖化血红蛋白(HBA1C)的差异,分析并发组患者发生2型糖尿病肾病合并心脑血管疾病的危险因素。结果:病程、饮食喜好、空腹血糖、同型半胱氨酸和糖化血红蛋白是老年2型糖尿病肾病并发心脑血管疾病的相关危险因素,而吸烟、收缩压和总胆固醇是老年2型糖尿病肾病并发心脑血管疾病的独立危险因素。结论:可以针对吸烟、病程、饮食喜好、血糖和糖化血红蛋白控制等因素进行干预控制和引导,以预防老年2型糖尿病肾病患者并发心脑血管疾病。
Objective: To explore some related risk factors of senile type 2 diabetic nephropathy with cardiovascular and cerebrovascular diseases, and to provide theoretical basis for clinical treatment and intervention. Methods: A total of 148 elderly patients with type 2 diabetic nephropathy with cardiovascular and cerebrovascular diseases were enrolled in this study. According to the type 2 diabetic nephropathy and cardiovascular and cerebrovascular disease grading criteria, 148 patients with diabetic nephropathy complicated with cardiovascular and cerebrovascular diseases were divided into two groups: No concurrent group of 202 cases. The data of the two groups were compared, such as sex ratio, age, number of smokers, number of drinking people, eating habits, eating habits and testing indexes such as body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (PP), course of disease, homocysteine (HCY), fasting blood glucose (FPG), triglyceride (TG), cholesterol (TC) and glycosylated hemoglobin (HBA1C) in patients with concurrent type 2 diabetes mellitus Risk factors for nephropathy with cardiovascular and cerebrovascular diseases. Results: The course of disease, dietary preference, fasting blood glucose, homocysteine and glycosylated hemoglobin were the risk factors of cardiovascular disease in elderly type 2 diabetic nephropathy. Smoking, systolic blood pressure and total cholesterol were the risk factors for type 2 diabetic nephropathy Independent risk factors for cerebrovascular disease. Conclusion: It is possible to control and guide the smoking, course of disease, dietary preference, blood glucose and glycosylated hemoglobin in order to prevent cardiovascular disease in elderly patients with type 2 diabetic nephropathy.