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系统性红斑狼疮(SLE)是一种自身免疫性疾病,几乎所有患者都有不同程度的肾累及,严重的可导致肾衰竭。新喋呤是由生物喋呤生物合成途径中的乌苷三磷酸形成,是多种神经递质酶羟化作用的辅因子,在多种疾病中可以见到新喋呤浓度增加。测定SLE 患者新喋呤水平,并探讨该指标在活动性疾病及疾病治疗中的作用。43名确诊的SLE 患者(36名女性,7名男性,年龄18～42岁)。按winfield 等制定的标准评价SLE 疾病的活动性,分成活动性和非活动性疾病。尿新喋呤和肌酐用反相
Systemic lupus erythematosus (SLE) is an autoimmune disease that affects almost all patients with varying degrees of renal involvement and can cause severe kidney failure. Neopterin is formed by the biosynthetic biosynthetic pathway of ubiquitin and is a cofactor for the hydroxylation of many neurotransmitters. Neopterin concentrations are seen in many diseases. Determination of neopterin levels in SLE patients, and explore the indicators in active disease and disease treatment. Forty-three confirmed patients with SLE (36 women, seven men, ages 18-42) were enrolled. According to Winfield and other standards developed by the evaluation of SLE disease activity, divided into active and inactive disease. Urine neopterin and creatinine with anti-phase