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本实验应用金黄地鼠胚胎(SHE)细胞,研究了低剂量~(60)Coγ线与雌性激素(EP)联合诱发细胞恶性转化的作用。实验结果表明两种因素联合应用,致癌作用加强。同时也证明,哺乳动物细胞的恶性转化是一个多阶段的生物学过程。
In this experiment, Golden Hamster Embryonic (SHE) cells were used to study the role of low-dose 60Co γ line and estrogen (EP) in the induction of malignant transformation of cells. The experimental results show that the combination of two factors has enhanced carcinogenesis. It also proves that the malignant transformation of mammalian cells is a multi-stage biological process.