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我院外科应用清胆注射液治疗急性胆道感 染有效率为80.7％,临床观察有清热解毒控制感染、利胆通下、疏通胆道和扶正救逆、纠正休克的功效,我们对清胆注射液的上述作用进行药理分析,以探讨其作用机理。清胆注射液由竹叶、柴胡、黄芩、龙胆草、蒲公英、金银花、连翘、丹参、姜半夏、枳实、大黄等组成。实验结果如下: (一)清热解毒控制感染的机理探讨 清胆对由伤寒菌苗引起的家兔体温升高有解热作用。体外和体内的抗内毒素实验,能使大肠杆菌内毒素含量明显减少,有减毒灭活作用。能降低由醋酸引起的小鼠腹腔毛
The effective rate of surgical treatment of acute biliary tract infection in our hospital is 80.7%. Clinical observations include the effects of heat-clearing, detoxifying, infection control, gallbladder ventilation, and biliary tract evacuation, and resuscitation, and correction of shock. We investigated the efficacy of Qingdan injection. The above-mentioned effects were analyzed pharmacologically to investigate its mechanism of action. Qingdan injection consists of bamboo leaves, Bupleurum, Scutellaria baicalensis, Gentian, dandelion, honeysuckle, forsythia, salvia miltiorrhiza, ginger pinellia, citrus aurantium, rhubarb and so on. The experimental results are as follows: (1) The mechanism of heat-clearing and detoxification to control infection The Qingdan has antipyretic effects on the temperature rise of rabbits caused by typhoid fever. In vitro and in vivo anti-endotoxin tests can significantly reduce the endotoxin content of E. coli and have a detoxification and inactivation effect. Reduces the abdominal hair of mice caused by acetic acid