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目的:观察头孢匹胺治疗下呼吸道感染的临床疗效。方法:对57例治疗组患者采用头孢匹胺进行治疗,62例对照组患者则单用头孢呋辛进行治疗,对比两组患者的临床疗效。结果:治疗组和对照组总有效率分别为87.7%和54.8%,两者差异具有显著性(P<0.05)。治疗组和对照组细菌学阴转率分别为91.9%和60.3%,差异具有显著性(P<0.05)。结论:头孢匹胺对多种细菌均敏感,是治疗下呼吸道感染是较为理想的药物,不良反应少见,值得临床应用。
Objective: To observe the clinical efficacy of cefpiramide in the treatment of lower respiratory tract infection. Methods: Fifty-seven patients in the treatment group were treated with cefpiramide, while 62 patients in the control group were treated with cefuroxime alone. The clinical efficacy was compared between the two groups. Results: The total effective rate of the treatment group and the control group was 87.7% and 54.8%, respectively, with significant difference (P <0.05). The bacteriological negative conversion rates of the treatment group and the control group were 91.9% and 60.3%, respectively, with significant difference (P <0.05). Conclusion: Cefpiramide is sensitive to many kinds of bacteria. It is an ideal drug for the treatment of lower respiratory tract infection. Its adverse reactions are rare and worthy of clinical application.