华法林是常用的口服抗凝血药 ,其抗凝血机制是竞争性拮抗维生素Ｋ的作用。本品在体外无效 ,在体内也需待已合成的凝血因子Ⅱ、Ⅶ、Ⅸ、Ⅹ耗竭后才能发挥作用 ,因此 ,急性抗凝可先与肝素合用。本品的药物相互作用比较复杂 ,若应用不当 ,不但达不到抗凝目的 ,反而会引起严重的出 Warfarin is a commonly used oral anticoagulant and its anticoagulant mechanism is a competitive antagonism of vitamin K. This product is ineffective in vitro, but also in vivo to be synthesized coagulation factors Ⅱ, Ⅶ, Ⅸ, Ⅹ exhausted to play a role, therefore, acute anticoagulation can be combined with heparin. This product is more complex drug interactions, if not properly applied, not only failed to achieve the purpose of anticoagulation, but will cause serious out