世界范围内,糖尿病患病率呈急剧上升趋势,而Ⅰ型糖尿病的患病率每年就增加约2%～5%。Ⅰ型糖尿病是由于T细胞介导的自身免疫破坏β细胞而引起,胰岛β细胞功能持续恶化是一种不可逆的过程。因此,科学家们将目光投向了替代和恢复胰岛β细胞功能治疗上。虽然胰岛细胞移植可以 Globally, the prevalence of diabetes shows a sharp upward trend, while the prevalence of type 1 diabetes increases by about 2% to 5% annually. Type I diabetes is caused by the destruction of beta cells by T cell mediated autoimmunity and the continued deterioration of pancreatic beta cell function is an irreversible process. As a result, scientists are turning their attention to functional therapy that replaces and restores islet beta cells. Although islet cell transplantation can be