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目的观察更昔洛韦治疗儿童病毒性心肌炎的临床疗效。方法将61例病毒性心肌炎患儿随机分成两组,A组28例为更昔洛韦治疗组,B组22例为对照组,两组均治疗6￣8d,治疗开始前及治疗后记录患儿体征、心肌酶谱、心电图变化。结果治疗组临床主要症状、体征、心电图、心肌酶谱恢复时间均优于对照组(P<001);治疗组与对照组疗效间差异有统计学意义(P<001)。结论更昔洛韦治疗儿童病毒性心肌炎疗效确切。
Objective To observe the clinical efficacy of ganciclovir in the treatment of viral myocarditis in children. Methods Sixty-one children with viral myocarditis were randomly divided into two groups. Group A (n = 28) was treated with ganciclovir, group B (n = 22) was treated as control. Both groups were treated for 6 ~ 8 days. Before and after treatment, Pediatric signs, myocardial enzymes, ECG changes. Results The main clinical symptoms, signs, electrocardiogram and myocardial enzyme recovery time in the treatment group were better than those in the control group (P <001). There was significant difference between the treatment group and the control group (P <001). Conclusion Ganciclovir treatment of viral myocarditis in children is effective.