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肺癌是当今世界各国常见的恶性肿瘤之一,也是最常见的死亡原因。尽管近十几年来在癌症的诊治方面已有许多新方法、新技术的问世,但肺癌的疗效仍不十分显著, 尤其是小细胞肺癌(Small Cell Lung Cancer,SCLC)。SCLC 占肺癌的10％-20％,是肺癌中分化程度最低,恶性程度高的一型。其生长速度快、并具有早期转移的特点。平均生存期在有、无广泛转移者分别为少于1年和18个月,极少数患者存活3年或更长,SCLC严重危害着人民的生命健康。因此,对SCLC病因及发病机制的研究显得尤为重要。
Lung cancer is one of the most common malignancies in the world today and the most common cause of death. Although there have been many new methods and new technologies in the diagnosis and treatment of cancer in recent decades, the efficacy of lung cancer is still not very significant, especially in Small Cell Lung Cancer (SCLC). SCLC accounts for 10% -20% of lung cancer, lung cancer is the lowest degree of differentiation, a high degree of malignant type. Its fast growth, and has the characteristics of early transfer. The average life expectancy is less than 1 year and 18 months for those with and without extensive metastasis, and very few patients have survived for 3 years or longer. SCLC seriously endangers people’s life and health. Therefore, the etiology and pathogenesis of SCLC research is particularly important.