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严重的晚期肝病最终多出现肝昏迷,死亡率甚高。急性暴发型肝炎进入肝昏迷者,存活率仅10～20%。目前采用的各种治疗措施,效果均不满意。因此,世界各国正在寻找新的治疗方法——人工肝脏,以使病人渡过危险期,争取肝脏有再生的机会,从而获得康复。在慢性肝病的终末期,一旦出现肝昏迷,预后恶劣需赖人工肝脏控制病情,为肝移植作准备。但是理想的人工肝脏必须具备以下条件:①维持蛋白质、脂肪和糖的正常代谢;②清除导致肝昏迷的有害物质;③纠正水、电解质的平衡紊乱及④解除肝脏再生的阻碍因子。近年来国外在这方面虽进行了积极的研究,设计并使用
Serious late liver disease eventually appear hepatic coma, the mortality rate is very high. Acute fulminant hepatitis into hepatic coma, the survival rate of only 10 to 20%. Currently used in a variety of treatment measures, the results are not satisfied. Therefore, all over the world are looking for a new treatment - artificial liver, so that patients through the dangerous period for the liver have a chance of regeneration, so as to be rehabilitated. In the terminal phase of chronic liver disease, once a hepatic coma occurs, the prognosis is poor and depends on the artificial liver to control the condition and prepare for liver transplantation. But the ideal artificial liver must have the following conditions: ① to maintain the normal metabolism of protein, fat and sugar; ② clear lead to hepatic coma harmful substances; ③ correct water and electrolyte balance disorders and ④ lift the liver regeneration block factor. In recent years, foreign countries have conducted active research, designed and used this aspect