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目的:研究运动诱发电位(MEP)检查对运动神经元病(MND)的临床诊断价值。方法:应用运动诱发电位(MEP)技术检查21例运动神经元病(MND)患者。结果:肌萎缩侧索硬化症(ALS)、原发性侧索硬化症(PLS)和进行性脊肌萎缩症(SPMA)中枢运动神经传导时间(CMCT)延长分别占87.50%、11%和15.0%,MEP异常率(包括潜伏期及CMCT延长)分别为95.0%,95.83%和5.0%。结论:MEP的主要价值是检查中枢运动传导功能,能为MND的诊断及其临床分型提供客观依据。
Objective: To investigate the value of motor evoked potential (MEP) in the diagnosis of motor neuron disease (MND). Methods: Twenty-one patients with motor neuron disease (MND) were examined with motor evoked potentials (MEP). Results: ALT, PLS and SPMA increased the motor nerve conduction time (CMCT) by 87.50%, 11% And 15.0% respectively. The MEP anomalies (including latency and CMCT extension) were 95.0%, 95.83% and 5.0% respectively. Conclusion: The main value of MEP is to check the central motor conduction function, which can provide an objective basis for the diagnosis of MND and its clinical classification.