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从“肝”着手,将与胆囊胆固醇结石密切相关且具有相似特性的“胆病及肝、肝胆气郁”病机与“胆病从肝论治”理论及以“胆汁发源地肝核受体LXRs/FXR→胆固醇/胆汁酸代谢→利于结石形成”这条胆汁成分代谢链相联系,推测后者可能即是前者的物质基础和发挥疗效的主要作用主线。文章拟从中医学理论基础及分子病理基础两方面来阐述二者的相关性,为胆固醇结石病的防治策略及丰富“胆病从肝论治”理论提供依据。
From the “liver” to proceed, will be closely related with the gallbladder cholesterol stones and have similar characteristics of “gallbladder and liver, liver and gallbladder qi” pathogenesis and “gall disease from the liver theory” and “theory” Bile origin of liver nuclear receptor LXRs / FXR → cholesterol / bile acid metabolism → conducive to the formation of stones, "the bile component of the metabolic chain linked to the latter may be that the former is the material basis and play a major role in the main effect line. This article intends to elaborate the correlation between the two on the basis of TCM theoretical foundation and molecular pathology, and provide the basis for the prevention and cure of cholesterol gallstone disease and its rich theory of gall disease from the liver.