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目的观察丙泊酚对腹腔镜下子宫肌瘤剔除术患者全身麻醉苏醒期躁动的影响。方法选取医院行腹腔镜下子宫肌瘤剔除术的患者92例作为研究对象,随机分为对照组和观察组,每组46例。对照组在建立气腹前采用七氟烷吸入维持麻醉,观察组采用丙泊酚与瑞芬太尼维持麻醉。记录2组患者麻醉起效时间、恢复时间以及拔管时间,采用Ramsay镇静评分对2组患者的镇静效果进行评估,并进行苏醒期躁动评估及麻醉效果评估。结果观察组恢复时间、拔管时间均明显短于对照组(P<0.01);观察组Ramsay镇静评分为(4.63±1.24)分,高于对照组的(3.37±1.20)分(P<0.01);观察组躁动发生率为15.22%,低于对照组的30.43%(P<0.05);观察组麻醉优良率为95.65%,高于对照组的84.78%(P<0.05)。结论丙泊酚联合瑞芬太尼对腹腔镜下子宫肌瘤剔除术患者全身麻醉苏醒期躁动的控制效果较好,且有利于缩短恢复时间和拔管时间,值得临床推广应用。
Objective To observe the effect of propofol on restlessness during general anesthesia in patients undergoing laparoscopic myomectomy. Methods A total of 92 patients undergoing laparoscopic myomectomy in our hospital were randomly divided into control group and observation group, with 46 cases in each group. In the control group, sevoflurane inhalation was used to maintain anesthesia before the establishment of pneumoperitoneum. The observation group was propofol and remifentanil to maintain anesthesia. The onset time of anesthesia, recovery time and extubation time were recorded in two groups. The sedation scores of two groups were evaluated by Ramsay sedation score, and the recovery of restlessness and anesthesia were evaluated. Results The recovery time and extubation time in the observation group were significantly shorter than those in the control group (P <0.01). The Ramsay sedation score in the observation group was (4.63 ± 1.24) points higher than that in the control group (3.37 ± 1.20) . The incidence of agitation in observation group was 15.22%, which was lower than that in control group by 30.43% (P <0.05). The excellent and good rate in observation group was 95.65%, which was 84.78% higher than that in control group (P <0.05). Conclusions Propofol combined with remifentanil has better control effect on restlessness of general anesthesia in patients undergoing laparoscopic myomectomy and is beneficial to shortening the recovery time and extubation time, which is worthy of clinical application.