目的:探讨无肝素血液透析在合并高度出血危险的透析患者中的应用及护理体会。方法:对53例合并活动性出血或有出血倾向的血透患者进行无肝素血液透析,并分别于血液透析前、透析结束后测定白陶土部分凝血活酶时间(KPTT),观察管道及透析器凝血情况、临床症状等变化。结果:53例患者应用无肝素血液透析214例次均成功,测定凝血时间118次,出血情况未加重。结论:无肝素血液透析对合并活动性出血或有出血倾向的血透患者效果满意、安全、可靠,不加重患者的出血现象。 Objective: To investigate the application and nursing experience of heparin-free hemodialysis in dialysis patients with high risk of bleeding. Methods: Fifty-three hemodialysis patients with active hemorrhage or hemorrhagic tendency were enrolled in this study. Before hemodialysis, the KPTT was measured after hemodialysis. The duration of hemodialysis Coagulation, clinical symptoms and other changes. Results: All of the 53 patients were successful in 214 cases without hemodialysis, the clotting time was 118, and the bleeding was not aggravated. Conclusion: Heparin-free hemodialysis is effective, safe and reliable for hemodialysis patients with active bleeding or bleeding tendency, and does not aggravate bleeding in patients.