报道大肠原发性恶性淋巴瘤４例，结合文献，对其发病率、诊断、病理特点、治疗及预后进行分析讨论。认为该病临床表现隐匿，易误诊；肿瘤浸润范围大，淋巴结转移率低。术中快速病理诊断应取材原发灶。预后与病期长短、肿瘤大小、浸润程度、淋巴结转移及组织类型关系密切。 Reported 4 cases of colorectal primary malignant lymphoma, combined with literature, analysis of the incidence, diagnosis, pathological features, treatment and prognosis. It is considered that the clinical manifestations of the disease are hidden and misdiagnosed; the extent of tumor invasion is large and the lymph node metastasis rate is low. Intraoperative rapid pathological diagnosis should be taken from the primary lesion. The prognosis is closely related to the length of the disease, tumor size, invasiveness, lymph node metastasis, and tissue type.