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动脉粥样硬化(Atherosclerosis,以下简称AS),是一种多因性疾病,其发展过程缓慢而复杂,按疾病发展过程中的阶段性,可将它分为AS的准备阶段和AS的形成阶段;再根据疾病过程中的因果转换律,又可将AS的病因相应分为“原始病因”和“继发病因”;原始致病因素复杂而繁多,但就其主要致病效应来说,不外乎为致脂肪代谢紊乱因素和致动脉管壁损伤因素,AS的“继发病因”是指血小板在动脉内膜上的粘附、聚集、释放反应和脂质向动脉内膜的“病理性入侵”;“原始病因”只使AS开始发生、并为其发展和形成准备好必要的“物质条件”和“管壁条件”,而“继发病因”才真正促使了AS特征性病变的形成,并与“原始病因”一道,最后完成AS的全过程.
Atherosclerosis (Atherosclerosis, hereinafter referred to as AS), is a multi-cause disease, its development process is slow and complex, according to the stages of disease development process, it can be divided into AS preparation stage and AS formation stage ; And then according to the disease process of causality conversion law, but also the causes of AS can be divided into “original cause” and “secondary cause”; the original risk factors are complex and numerous, but in terms of its main pathogenic effects, not Outside the fat metabolism disorders and factors that lead to the injury of the arterial wall, AS “secondary cause” refers to platelet adhesion in the intima of the arteries, aggregation, release and lipid into the arterial intima of the “pathological Invasion ”;“ original cause ”only makes AS begin to occur and prepares necessary“ material conditions ”and“ wall conditions ”for its development and formation, while“ secondary cause ”really promotes the formation of AS characteristic lesions , And together with the “original cause”, the final completion of the entire process of AS.