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目的:比较丁咯地尔与脉络宁治疗脑梗死的疗效。方法:60例脑梗死病人,其中30例采用丁咯地尔200mg加入5%葡萄糖注射液500mL,静脉滴注(静滴),qd,14d为一个疗程。另30例为对照组,采用脉络宁20mL加入5%葡萄糖注射液500mL,静滴,qd,14d为一个疗程。结果:丁咯地尔组总有效率87%,显效率63%。脉络宁组总有效率64%,显效率30%(P<0.05)。丁咯地尔对脑循环动力学有显著改善(P<0.01)。该药不良反应较少。结论:丁咯地尔治疗脑梗死的疗效优于脉络宁。
Objective: To compare the efficacy of buflomedil and Mailuoning in treating cerebral infarction. Methods: 60 patients with cerebral infarction, of which 30 cases of buflomedil 200mg added 5% glucose injection 500mL, intravenous infusion (intravenous drip), qd, 14d for a course of treatment. The other 30 cases as control group, the Mailuoning 20mL adding 5% glucose injection 500mL, intravenous drip, qd, 14d for a course of treatment. Results: Buflomedil group, the total effective rate was 87%, markedly effective rate of 63%. Mailuoning group total effective rate 64%, markedly efficient 30% (P <0.05). Buflomedil had a significant improvement in cerebral circulation kinetics (P <0.01). The drug adverse reactions less. Conclusion: Buflomedil is superior to Mailuoning in the treatment of cerebral infarction.