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糖尿病性水疱病是糖尿病的一种少见皮肤合并症,文献报道不多,现将临床所见11例综合文献报告7例,总结如下:本组11例,男5例,女6例,年龄在42～72岁,中位数57岁.除1例因肢体麻木合并水疱病住院后才确诊为糖尿病外,其余10例糖尿病病程为4～20年,平均12年,已死亡3例,占27.2%.糖尿病治疗情况:11例病人均为非胰岛素依赖型,4例在应激时出现酮症酸中毒,加用普通胰岛素治疗,时间2～8天,均为小剂量6～12u/日,11例病人治疗期间,间断或长期口服降血糖药物,控制饮食,常用降糖药物为优降糖、降糖灵、糖适平、达美康中药等治疗.合并水疱病时空腹血糖8.8～27.2mmo/L,平均为15.27mmol/L,尿糖(++～+++).水疱出现的部位:拇趾2例,足背外侧4例,拇指5例,其中有3例上述部位反复出现.
Diabetic blister disease is a rare case of diabetic skin complications, reported in the literature is not much, now the clinical findings of 11 cases of comprehensive literature reported in 7 cases, summarized as follows: The group of 11 patients, 5 males and 6 females, aged 42-72 years old, with a median of 57. Except for one case of diabetes mellitus diagnosed as diabetic numbness due to limb numbness combined with blister disease, the remaining 10 cases had diabetes for 4 to 20 years, with an average of 12 years and 3 died, accounting for 27.2% %. Treatment of diabetes: 11 patients were non-insulin-dependent, 4 cases of ketoacidosis when stress, plus ordinary insulin treatment, time 2 to 8 days, are low-dose 6 ~ 12u / day, 11 cases of patients during treatment, intermittent or long-term oral hypoglycemic drugs to control the diet, commonly used hypoglycemic agents for the hypoglycemic, hypoglycemic, glucose and Pingmei, such as the United States and other Chinese medicine treatment.When combined blister disease, fasting blood glucose 8.8 ~ 27.2mmo / L, with an average of 15.27mmol / L, urine sugar (++ ~ +++) .The blister appeared in 2 cases: the big toe, the dorsal outer side in 4 cases, the thumb in 5 cases, of which 3 cases of the above parts recur.