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对56例进行性前列腺癌的临床特征及治疗进行总结:①膀胱出口处梗阻占83.9%;睾丸去势术和内分泌治疗后不能完全解除梗阻症状。②输尿管梗阻引起的肾积水占14.3%,与前列腺癌的浸润有关;及时解除梗阻如行经皮肾造瘘术能挽救肾功能和延长患者的生命。③骨转移往往会引起进行性前列腺癌患者产生骨痛和病理性骨折;使用放射性磷(~(32)P)和甲状旁腺素作媒介物能取得满意的疗效。④脊髓压迫是进行性前列腺癌的致残表现,早期出现会阴、骶尾部的感觉障碍或丧失和放射性疼痛;常用椎板减压术进行治疗,但难以阻止病情恶化。⑤直肠梗阻、凝血机制紊乱,应用酮康唑效果良好。
Clinical characteristics and treatment of 56 cases of progressive prostate cancer were summarized: ① Bladder outlet obstruction accounted for 83.9%; testicular ovariectomy and endocrine therapy can not completely relieve the symptoms of obstruction. ② ureteral obstruction caused by hydronephrosis accounted for 14.3%, and the infiltration of prostate cancer; promptly relieve the obstruction such as percutaneous nephrostomy can save kidney function and prolong the life of patients. ③ bone metastases often cause progressive prostate cancer patients have bone pain and pathological fractures; use of radioactive phosphorus (~ (32) P) and parathyroid hormone as a vehicle can achieve satisfactory results. ④ spinal cord compression is a manifestation of progressive prostate cancer, early perineal, sacrococcygeal sensory disturbances or loss and radiological pain; commonly used laminoplasty for treatment, but difficult to stop the deterioration of the disease. ⑤ rectal obstruction, coagulation disorders, the effect of ketoconazole good.