论文部分内容阅读
此项研究通过测定尿液中烟碱与可替宁含量来评估卷烟烟气与环境烟气 (ETS)对人体的影响。共收集了 1 2 9个尿样 ,这些尿样是根据人的性别、年龄、吸烟年限、平均日消耗烟支数和家庭吸烟人数等特征进行采集的。采集后的尿样先通过Extrelut柱 ,然后用GC/NPD来分析尿样中烟碱和可替宁的含量。在吸烟者的尿样中 ,烟碱和可替宁平均浓度分别为5 .38μg/ml和 3.1 4μg/ml。男性不吸烟者尿液中烟碱和可替宁的平均浓度分别为 0 .1 8μg/ml和0 .0 7μg/ml。吸烟者尿液中烟碱和可替宁含量取决于日消耗烟支数 ,而且 ,吸烟者尿液中烟碱含量和日平均消耗烟支数有直接关系。非吸烟者尿样中烟碱和可替宁来源可能为食物、饮料和ETS。研究结果表明 ,家庭中吸烟者的人数对不吸烟者尿液中烟碱和可替宁浓度的增加没有影响。
This study evaluated the effects of cigarette smoke and ambient flue gas (ETS) on the human body by measuring nicotine and cotinine levels in urine. A total of 1,29 urine samples were collected. These urine samples were collected based on such factors as gender, age, smoking duration, average daily consumption of cigarettes and number of smokers in the household. The collected urine sample is passed through an Extrelut column and analyzed by GC / NPD for nicotine and cotinine levels in the urine. Nicotine and cotinine average concentrations were 5.38 μg / ml and 3.1 4 μg / ml, respectively, in the smoker’s urine sample. The average concentrations of nicotine and cotinine in urine of male non-smokers were 0.18 μg / ml and 0.07 μg / ml, respectively. The level of nicotine and cotinine in the urine of smokers depends on the daily consumption of cigarettes. Moreover, the nicotine level in the urine of smokers is directly related to the average daily consumption of cigarettes. Nicotine and cotinine sources in nonsmokers urine may be food, beverages and ETS. The results show that the number of smokers in the family has no effect on the increase in nicotine and cotinine concentrations in the urine of non-smokers.