血栓溶解疗法是治疗闭塞性血管病的一条新途径,近年来已广泛应用于临床,现就某些研究进展情况综述如下。概念和机理一、1893年Dastre发现血液凝块有自然溶解的现象,并称之为“纤溶现象”。在正常人的血液中,纤维蛋白的溶解与抗溶解是处于动态平衡的。当使用某种药物,破坏这种动态平衡,提高纤溶活性,使纤维蛋白溶解的方法,就称“血栓溶解疗法”。二、溶血栓药物的作用并非直接使血栓溶解。正常情况下,如图所示,血液中一般没有 Thrombolytic therapy is a new approach to the treatment of occlusive vascular disease, which has been widely used in clinical practice in recent years. The progress of some studies is summarized as follows. Concepts and Mechanisms First, in 1893 Dastre found that blood clot naturally dissolved phenomenon, and called “fibrinolytic phenomenon.” In normal people’s blood, fibrin is dissolved and dissolved in a dynamic equilibrium. Thrombolytic therapy is called “thrombolytic therapy” when using a drug that disrupts this homeostasis, increases fibrinolytic activity, and fibrinolytic. Second, the role of thrombolytic drugs is not directly to thrombolytic. Under normal circumstances, as shown, the blood is generally not