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目的为了了解长春地区儿童甲型肝炎自然感染情况。方法采用竞争性抑制ELISA法检测甲型肝炎抗体。结果对417名儿童进行甲肝抗体检测,甲肝病毒抗体-IgG阳性176例,自然感染率为42.21%,学龄前儿童与学龄后儿童自然感染率分别为36.47%和63.64%,统计学分析差异显著,表明甲型肝炎的自然感染率学龄后儿童甲型肝炎的易感率较高。结论0~6岁儿童抗体水平较低,随着年龄的增长,甲肝抗体阳性率呈现上升趋势。
Objective To understand the natural infection of hepatitis A in children in Changchun area. Methods Hepatitis A antibody was detected by competitive inhibition ELISA. Results A total of 417 children were tested for anti-Hepatitis A antibody. 176 cases were positive for IgG antibody-IgG, with a natural infection rate of 42.21%. The natural infection rates of preschool children and post-school children were 36.47% and 63.64% respectively. Statistical analysis showed significant differences Hepatitis A Natural Infection Rate Hepatitis A is more likely to be susceptible to hepatitis A in school-age children. Conclusion The level of antibody in children aged 0-6 years is low. With the increase of age, the positive rate of anti-HBs is on the rise.