目的探讨导管内定向溶栓治疗突发性耳聋的方法及临床疗效。方法经导管介入选择性应用尿激酶治疗突发性耳聋5例,其中男3例,女2例,年龄30-68岁。结果 5例患者中治愈3例(60％),显效1例(20％),有效1例(20％),无效0例(0％),术后均无任何并发症。结论经导管介入治疗突发性耳聋具有良好的临床疗效及安全性,可在临床加以推广。 Objective To investigate the method and clinical efficacy of directional catheterization for sudden deafness treatment. Methods 5 cases of sudden deafness were treated with catheterization of urokinase, including 3 males and 2 females, aged 30-68 years. Results Among 5 patients, 3 cases were cured (60%), 1 case (20%) was markedly effective, 1 case (20%) effective and 0 (0%) ineffective. No complications were found after operation. Conclusion Transcatheter intervention for sudden deafness has good clinical efficacy and safety, which can be popularized clinically.