目的　探讨成体干细胞 (AS细胞 )的分化潜能性及在临床修复重建中应用的可能。方法　检索医学和生物医学文献数据库中关于 AS细胞研究的相关报道 ,并对 AS细胞的最新研究进展作简要总结。结果　 AS细胞存在于成体的各种组织中 ,具有自我更新能力和分化潜能性 ;部分成体干细胞 ,如骨髓、皮肤、肝及脂肪等组织中的 AS细胞 ,具有多向分化潜能 ,可向无关组织类型的成熟细胞横向分化 ;AS细胞是组织更新与修复的起源细胞 ,且与肿瘤的发生和衰老密切相关。结论　 AS细胞具有多向分化潜能 ,在创伤修复等再生医学中有广阔的应用前景 Objective To investigate the differentiation potential of adult stem cells (AS cells) and its possible application in clinical repair and reconstruction. Methods Retrieve relevant reports on AS cell research from the medical and biomedical literature databases and briefly summarize the latest research progress on AS cells. Results AS cells were found in adult tissues and had self-renewal and differentiation potential. AS cells in some adult stem cells, such as bone marrow, skin, liver and adipose tissue, had multidirectional differentiation potential and could differentiate into unrelated tissues Type of mature cells transverse differentiation; AS cells are the cells of origin of tissue regeneration and repair, and with the occurrence and aging of the tumor are closely related. Conclusions AS cells have the potential of multi-directional differentiation and have broad application prospects in regenerative medicine such as wound healing