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目的:探讨玻璃体切除术联合丙羟基泼尼松龙(TA)玻璃体腔内注药治疗外伤性眼内炎的临床效果。方法:回顾性分析因外伤性眼内炎行玻璃体切除手术治疗的患者22例(22眼),其中行玻璃体切除并TA和万古霉素玻璃体腔内注药11例(Ⅰ组),玻璃体切除并万古霉素玻璃体腔内注药11例(Ⅱ组)。术前视力无光感至眼前指数。对比两组术后1周视力、炎症消退时间等。结果:术后1周患眼视力无光感至0.3,20眼(90.9%)术后1周视力有不同程度提高。Ⅰ组11眼中10眼有效(90%),Ⅱ组11眼中5眼有效(45%),差异具有显著性意义(P<0.05)。术后炎症反应消退时间Ⅰ组为(4.38±1.95)d,Ⅱ组为(6.83±1.97)d,两组比较差别有显著性意义(P<0.05)。22眼中,术后有5眼高眼压,2眼假性前房积脓,无严重其它并发症。结论:TA玻璃体腔注射在外伤性眼内炎玻璃体切除术中的应用对该病的治疗有较好的效果。
Objective: To investigate the clinical effect of vitrectomy combined with propofol prednisolone (TA) intravitreal injection on traumatic endophthalmitis. Methods: Twenty-two patients (22 eyes) underwent vitrectomy for traumatic endophthalmitis were retrospectively analyzed. Eleven patients (group Ⅰ) underwent vitrectomy with intravitreal injection of TA and vancomycin, and vitrectomy Vancomycin intravitreal injection of 11 cases (Ⅱ group). Preoperative visual acuity to immediate index. Visual acuity, inflammation subsidence time and so on were compared between two groups after 1 week. Results: One week after operation, no visual acuity was found in 0.3,20 eyes (90.9%). Visual acuity improved to some extent in one week after operation. Among 11 eyes of group Ⅰ, 10 eyes were effective (90%), while 11 eyes of group Ⅱ (5 eyes) were effective (45%). The difference was significant (P <0.05). Postoperative inflammatory response subsided time was (4.38 ± 1.95) days in group Ⅰ, and (6.83 ± 1.97) days in group Ⅱ. There was significant difference between the two groups (P <0.05). In 22 eyes, there were 5 eyes with intraocular hypertension after operation and 2 eyes with pseudo-hyphema, without serious complications. Conclusion: The application of TA intravitreal injection in vitrectomy of traumatic endophthalmitis has a good effect on the treatment of this disease.