心脏病发作与中风是最常见的致死性病因。在急性起病时,补体介导的炎症反应可加重心肌或脑组织的缺血坏死损伤,若发生大面积梗死将直接导致发病率和死亡率剧增,而残留的大块瘢痕亦可能产生远期的不良预后。因此,临床上亟需一种新的保护心脏与神经组织的治疗手段出现。早先的研 Heart attacks and strokes are the most common fatal causes. In acute onset, complement-mediated inflammatory response can aggravate ischemic necrosis of myocardium or brain tissue, and a large area infarction will directly lead to a sharp increase in morbidity and mortality, while the residual large scar may also be generated far Poor prognosis. Therefore, the clinical need for a new protection of heart and nerve tissue treatment emerged. Earlier research