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当今世界约有200万乙型肝炎病毒携带者,这些人均有发展成慢性肝炎、肝硬化及肝细胞癌的危险.而且可能为疾病的传染源.所以需要有效的治疗.抗病毒治疗治疗慢性HBV感染的目的是清除复制及非复制型病毒,从而防止HBV感染的进一步传播及出现进行性肝损和肝细胞癌(HCC).HBeAg阳性患者体内有进行复制的病毒,并有活动性肝病,所以使用抗病毒治疗得益最大.若在慢性HBV感染的早期开始治疗,在整合有HBV基因组的肝细胞克隆尚未稳定建立前进行,则HBV可完全清除,HBsAg转阴而抗-
There are about 2 million Hepatitis B virus carriers in the world today, all of whom are at risk of developing chronic hepatitis, cirrhosis and hepatocellular carcinoma, and may be the source of the disease, so effective treatment is needed Antiretroviral therapy for the treatment of chronic HBV The purpose of the infection is to remove both replicating and non-replicating viruses, thus preventing the further spread of HBV infection and developing progressive liver damage and hepatocellular carcinoma (HCC) .HebeAg-positive patients have replication-competent viruses and have active liver disease Using antiretroviral therapy benefit the most if early treatment of chronic HBV infection in the integration of the HBV genome of hepatocyte clones have not been established before the stable, then the HBV can be completely eliminated, HBsAg negative and anti -