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中性粒细胞硷性磷酸酶(简称NAP)的检查,多年来主要用于粒细胞型白血病与类白血病反应的鉴别诊断。在急、慢性粒细胞型白血病时,NAP均明显降低;而在粒细胞型类白血病反应时,NAP明显升高。1964年吕雁群等曾报道23例烧伤病员NAP的变化,指出烧伤合并败血症时,NAP积分平均高达228分,并且在血培养阳性前2天半出现;烧伤毒血症时,NAP积分平均高达175分,并且较临床症状提前2~3天出现。我们观察了100例战伤感染的NAP变化,现报道如下。
Neutrophil alkaline phosphatase (NAP) for many years, mainly for the differential diagnosis of leukemia and leukemia response. In acute and chronic myeloid leukemia, NAP were significantly reduced; while in the response to granulocytic leukemia, NAP was significantly higher. In 1964, Lv Yanqun et al. Reported the changes of NAP in 23 cases of burn patients. It was pointed out that NAP scores were as high as 228 at burn combined with septicemia, and appeared 2 and a half days before blood culture positive. On the other hand, when burn septicemia occurred, NAP scores averaged as high as 175 , And 2 to 3 days earlier than clinical symptoms appear. We observed changes in NAP in 100 cases of war-wound infection and are reported below.